Antiretroviral treatment adherence and its correlates in Addis Ababa, Ethiopia

Tadios, Yonas and Davey, Gail (2006) Antiretroviral treatment adherence and its correlates in Addis Ababa, Ethiopia. Ethiopian Medical Journal, 44 (3). pp. 237-244. ISSN 0014-1755

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Abstract

OBJECTIVE

To assess the degree of adherence with highly active antiretroviral therapy (HAART), and its correlates among adults with HIV/AIDS in Addis Ababa.

PATIENTS AND METHODS

Cross-sectional survey of consecutive patients attending three ART centers in Addis Ababa complemented by semi-structured audiotaped in-depth interviews with 10 purposively sampled patients on HAART Treatment adherence was defined as self-report of taking > or =95% of therapy correctly in a specified time period, depression measured using Beck's depression inventory, clinical data recorded by reviewing patients' charts, and knowledge about HAART assessed by questions in "Yes"/"No "format.

RESULTS

431 patients on HAART responded 81.2% of patients were > or =95% adherent by self report in the week before the assessment. The major reasons for non-adherence were: being too busy or simply forgot (33.9%) and being away from home (27.5%). Correlates of adherence included having regular follow-up, not being depressed having no side effects, a regimen that fitted the daily routine and satisfaction with the relationship with doctors.

CONCLUSIONS

Self-reported adherence in our study was higher than that seen in developed countries. Recommendations to improve adherence include: provision of regular follow-up for patients, management of depression, forewarning of side effects of HAART, and creating medication schedules appropriate to patients' daily routines.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Global Health and Infection
Subjects: R Medicine > RC Internal medicine > RC0251 Constitutional diseases (General)
Depositing User: Gail Davey
Date Deposited: 09 Jun 2014 13:27
Last Modified: 03 Aug 2017 17:51
URI: http://sro.sussex.ac.uk/id/eprint/48217
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