Data-driven honeybee antennal lobe model suggests how stimulus-onset asynchrony can aid odour segregation

Nowotny, Thomas, Stierle, Jacob S, Galizia, C Giovanni and Szyszka, Paul (2013) Data-driven honeybee antennal lobe model suggests how stimulus-onset asynchrony can aid odour segregation. Brain Research, 1536. pp. 119-134. ISSN 0006-8993

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Abstract

Insects have a remarkable ability to identify and track odour sources in multi-odour backgrounds. Recent behavioural experiments show that this ability relies on detecting millisecond stimulus asynchronies between odourants that originate from different sources. Honeybees,
Apis mellifera , are able to distinguish mixtures where both odourants arrive at the same time (synchronous mixtures) from those where odourant onsets are staggered (asynchronous mixtures) down to an onset delay of only 6 ms. In this paper we explore this surprising ability in a model of the insects' primary olfactory brain area, the
antennal lobe. We hypothesize that a winner-take-all inhibitory network of local neurons in the antennal lobe has a symmetry-breaking effect, such that the response pattern in projection neurons to an asynchronous mixture is different from the response pattern to the corresponding synchronous mixture for an extended period of time beyond the initial odourant onset where the two mixture conditions actually differ. The prolonged difference between response patterns to synchronous and asynchronous mixtures could facilitate odour segregation in downstream circuits of the olfactory pathway. We present a detailed data-driven model of the bee antennal lobe that reproduces a large data set of experimentally observed physiological odour responses, successfully implements the hypothesised symmetry-breaking mechanism and so demonstrates that this mechanism is consistent with our current knowledge of the olfactory circuits in the bee brain.

Item Type: Article
Schools and Departments: School of Engineering and Informatics > Informatics
Subjects: Q Science > QA Mathematics > QA0075 Electronic computers. Computer science
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
Depositing User: Thomas Nowotny
Date Deposited: 03 Mar 2014 15:56
Last Modified: 06 Mar 2017 18:21
URI: http://sro.sussex.ac.uk/id/eprint/47660

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Project NameSussex Project NumberFunderFunder Ref
Green BrainUnsetEPSRCEP/J019690/1