Evolving controversies and challenges in the management of opportunistic infections in HIV-seropositive individuals

Dockrell, David H, Edwards, Simon, Fisher, Martin, Williams, Ian and Nelson, Mark (2011) Evolving controversies and challenges in the management of opportunistic infections in HIV-seropositive individuals. Journal of Infection, 63 (3). pp. 177-186. ISSN 1532-2742

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Abstract

The British HIV Association, in association with the British Infection Association, has produced guidelines on the management of opportunistic infections in individuals living with HIV. Opportunistic infections remain a major clinical challenge emphasising the key role of early testing and getting individuals on antiretroviral therapy before their CD4 T-cell count drops to levels that put individuals at risk of opportunistic infection. We emphasise the changing pattern of opportunistic infections and the importance of considering what constitutes an opportunistic infection in the era of effective combination antiretroviral therapy as well as the increasing burden of geographically restricted infections. Key areas of when to safely stop prophylaxis against opportunistic infection and when to start antiretroviral therapy after treatment of an opportunistic infection are discussed.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine > RA0643 Communicable diseases and public health > RA0644 Individual diseases or groups of diseases, A-Z > RA0644.A25 AIDS. HIV infections
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Depositing User: Ellen Thomas
Date Deposited: 14 Feb 2014 12:17
Last Modified: 14 Feb 2014 12:17
URI: http://sro.sussex.ac.uk/id/eprint/47512
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