Cell impedance of cancer cells: towards novel diagnostic and therapeutic selection methods

Duan, Wei (2013) Cell impedance of cancer cells: towards novel diagnostic and therapeutic selection methods. Masters thesis (MPhil), University of Sussex.

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Abstract

Cancer is caused by genetic damage to DNA, this mutant cell then grows in an uncontrolled manner in the organism. Breast cancer is a one of most common cancers among women. Early detection of breast cancer is the most important way to reduce the mortality rate. Impedance measure is one of the
methods for breast cancer detection.

Apoptosis is programmed cell death and plays an essential role in protection of both tissues and organisms. There are many ways to detect apoptosis such as flow cytometry of PI stained cells, caspase assays and impedance measurements.

The aim of this project is to use cell impedance system (CIS) to ask whether breast cancer cell lines and a normal breast cell line can be distinguished. Furthermore, whether cells undergoing apoptosis in response to the chemotherapy reagent Etoposide can be identified using CIS.

Item Type: Thesis (Masters)
Schools and Departments: School of Life Sciences > Biochemistry
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology Including cancer and carcinogens > RC0280 By region, system, or organ of the body, or type of tumor, A-Z > RC0280.B8 Breast. Mammary glands
Depositing User: Library Cataloguing
Date Deposited: 31 May 2013 05:59
Last Modified: 08 Sep 2015 14:49
URI: http://sro.sussex.ac.uk/id/eprint/44414

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