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Cell impedance of cancer cells: towards novel diagnostic and therapeutic selection methods

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posted on 2023-06-08, 14:45 authored by Wei Duan
Cancer is caused by genetic damage to DNA, this mutant cell then grows in an uncontrolled manner in the organism. Breast cancer is a one of most common cancers among women. Early detection of breast cancer is the most important way to reduce the mortality rate. Impedance measure is one of the methods for breast cancer detection. Apoptosis is programmed cell death and plays an essential role in protection of both tissues and organisms. There are many ways to detect apoptosis such as flow cytometry of PI stained cells, caspase assays and impedance measurements. The aim of this project is to use cell impedance system (CIS) to ask whether breast cancer cell lines and a normal breast cell line can be distinguished. Furthermore, whether cells undergoing apoptosis in response to the chemotherapy reagent Etoposide can be identified using CIS.

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  • Published version

Pages

107.0

Department affiliated with

  • Biochemistry Theses

Qualification level

  • masters

Qualification name

  • mphil

Language

  • eng

Institution

University of Sussex

Full text available

  • Yes

Legacy Posted Date

2013-05-31

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