Atypical herpes type 2 encephalitis associated with normal MRI imaging

Harrison, N A, MacDonald, B K, Scott, G and Kapoor, R (2003) Atypical herpes type 2 encephalitis associated with normal MRI imaging. Journal of Neurology, Neurosurgery, and Psychiatry, 74 (7). pp. 974-976. ISSN 0022-3050

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Abstract

We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range of clinical presentations that may be associated with herpes simplex encephalitis and emphasises the value of PCR for herpes simplex virus in the investigation of encephalitis regardless of imaging findings

Item Type: Article
Keywords: POLYMERASE-CHAIN-REACTION; SIMPLEX VIRUS TYPE-1; CEREBROSPINAL-FLUID; VIDARABINE; ACYCLOVIR; THERAPY; CSF; DNA
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine > R Medicine (General) > R895 Medical physics. Medical radiology. Nuclear medicine
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
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Depositing User: Hazelle Woodhurst
Date Deposited: 27 Nov 2012 15:04
Last Modified: 26 Sep 2017 11:43
URI: http://sro.sussex.ac.uk/id/eprint/43068
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