Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis

Strong, Michael J, Grace, Gloria M, Freedman, Morris, Lomen-Hoerth, Cathy, Woolley, Susan, Goldstein, Laura H, Murphy, Jennifer, Shoesmith, Christen, Rosenfeld, Jeffery, Leigh, P Nigel, Bruijn, Lucie, Ince, Paul and Figlewicz, Denise (2009) Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 10 (3). pp. 131-46. ISSN 1471-180X

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Abstract

Amyotrophic lateral sclerosis (ALS) is increasingly recognized to be a multisystem disorder which includes both clinical and neuropathological features of a frontotemporal lobar degeneration (FTLD). In order to provide a common framework within which to discuss the characteristics of the cognitive and behavioural syndromes of ALS, and with which to conduct clinical and neuropathological research, an international research workshop on frontotemporal dementia (FTD) and ALS was held in London, Canada in June 2007. The recommendations arising from this research workshop address the requirement for a concise clinical diagnosis of the underlying motor neuron disease (Axis I), defining the cognitive and behavioural dysfunction (Axis II), describing additional non-motor manifestations (Axis III) and identifying the presence of disease modifiers (Axis IV)

Item Type: Article
Keywords: Genetics, neuropathology, dementia
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry > RC0346 Neurology. Diseases of the nervous system Including speech disorders
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Depositing User: Patricia Butler
Date Deposited: 15 Nov 2012 15:06
Last Modified: 25 Sep 2017 13:50
URI: http://sro.sussex.ac.uk/id/eprint/42506
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