Frontoparietal activity with minimal decision and control in the awake macaque at 7 T

Stoewer, Steffen, Ku, Shih-Pi, Goense, Jozien, Steudel, Thomas, Logothetis, Nikos K, Duncan, John and Sigala, Natasha (2010) Frontoparietal activity with minimal decision and control in the awake macaque at 7 T. Magnetic Resonance Imaging, 28 (8). pp. 1120-1128. ISSN 0730-725X

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Abstract

Previous imaging work has identified a frontoparietal network in the human brain involved in many different cognitive functions, as well as in simple updates of attended information. To determine whether a similar network is present in the monkey brain and direct future electrophysiological recordings, we examined the activation of frontoparietal areas during visual stimulation in the awake, fixating monkey. We measured activity with BOLD fMRI in three animals and analyzed the data individually for each animal and at group level. We found reliable activations in lateral prefrontal and parietal areas, even though task-related decision making was minimal, as a response to simple update of visual information. These activations were significant for each individual animal, as well as at group level. Similar to human imaging results the update of visual input was enough to activate an extensive network of frontoparietal cortex in the macaque brain, a network which is normally associated with complex cognitive control processes

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry > RC0346 Neurology. Diseases of the nervous system Including speech disorders
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Depositing User: Hazelle Woodhurst
Date Deposited: 14 Nov 2012 12:32
Last Modified: 26 Sep 2017 11:54
URI: http://sro.sussex.ac.uk/id/eprint/42378
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