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Parallel evolution of Bt toxin resistance in Lepidoptera

journal contribution
posted on 2023-06-08, 09:59 authored by Neil CrickmoreNeil Crickmore, Francisco Badenes-Pérez, Simon Baxter, David Heckel, Chris Jiggins, Wendy Kain, Anna Morrison, Heiko Vogel, Ping Wang
Despite the prominent and worldwide use of Bt insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.

History

Publication status

  • Published

Journal

Genetics

ISSN

0016-6731

Publisher

Genetics Society of America

External DOI

Issue

2

Volume

189

Page range

675-679

Department affiliated with

  • Biochemistry Publications

Notes

Part of a multi-institute project to be identify the mechanism of resistance of major pest insects to the Bacillus thuringiensis biological pesticide.

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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