Cell signaling: The BRCT domain: signaling with friends?

Caldecott, Keith (2003) Cell signaling: The BRCT domain: signaling with friends? Science, 302 (5645). pp. 579-580. ISSN 0036-8075

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Abstract

The tandem BRCT domains of the tumor suppressor protein BRCA1 are thought to contribute to this protein's function in the cellular response to DNA damage. In his Perspective, Caldecott discusses new work ( Yu et al., Manke et al.) showing that the BRCT domains of BRCA1 and of other proteins bind specifically to phosphorylated amino acids in their protein partners.

Item Type: Article
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User: Keith Caldecott
Date Deposited: 06 Feb 2012 21:25
Last Modified: 30 Jul 2012 08:49
URI: http://sro.sussex.ac.uk/id/eprint/31196
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