Studies towards a total synthesis of kainic acid

Greenwood, E S, Hitchcock, P B and Parsons, P J (2003) Studies towards a total synthesis of kainic acid. Tetrahedron, 59 (18). pp. 3307-3314. ISSN 0040-4020

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Abstract

The preparation of the fused bicycle 14 is reported together with its photocyclisation to the dioxinone 2. Base induced fragmentation of the photoadduct 15 formed exclusively in the aforementioned photocylisation, followed by Wittig methylenation gave the kainoid derivative 18.

Item Type: Article
Additional Information: All synthetic work carried at Sussex and directed by the principle author PJP, all authors are from Sussex. Novel approach to the synthesis of excitatory amino acids.
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Philip Parsons
Date Deposited: 06 Feb 2012 21:17
Last Modified: 30 Mar 2012 08:34
URI: http://sro.sussex.ac.uk/id/eprint/30629
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