Polar assembly in a designed protein fiber

Smith, Andrew M, Acquah, Steve F A, Bone, Neil, Kroto, Harold W, Ryadnov, Maxim G, Stevens, Marryat S P, Walton, David R M and Woolfson, Derek N (2005) Polar assembly in a designed protein fiber. Angewandte Chemie International Edition, 44 (2). pp. 325-328. ISSN 1433-7851

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Abstract

Bioinspiration: Polar assembly (a feature of many natural protein-based fibrous structures, such as actin, microtubules, intermediate filaments, and collagens) is demonstrated in a straightforward, synthetic, peptide-based fiber system of de novo design (see false-color confocal-microscope image of fibers). This finding opens up possibilities for engineering self-assembling soft materials from the bottom up and with nano-to-microscale precision.

Item Type: Article
Additional Information: HK jointly supervised SA with DW and contributed to the experimental design led by and in collaboraton with DW (now at Bristol) and co-authored the paper, all authors are from Sussex. First self asembly of protein fibres based on coiled coli motifs
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Neil MacIntyre Bone
Date Deposited: 06 Feb 2012 20:41
Last Modified: 07 Jun 2012 09:25
URI: http://sro.sussex.ac.uk/id/eprint/27434
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