TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage

Zeng, Zhihong, Cortes-Ledesma, Felipe, El-Khamisy, Sherif and Caldecott, Keith W (2010) TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage. Journal of Biological Chemistry, 286 (1). pp. 403-409. ISSN 0021-9258

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Item Type: Article
Additional Information: GDSC338
Keywords: Cancer Therapy, DNA Damage, DNA Repair, DNA Topoisomerase Phosphodiesterases
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology Including cancer and carcinogens
Depositing User: Gee Wheatley
Date Deposited: 26 Nov 2010
Last Modified: 07 Mar 2017 06:10
URI: http://sro.sussex.ac.uk/id/eprint/2554
Google Scholar:10 Citations

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