Recent Advances in the Discovery of Selective AMPA Receptor Positive Allosteric Modulators

Ward, Simon E and Harries, Mark (2010) Recent Advances in the Discovery of Selective AMPA Receptor Positive Allosteric Modulators. Current Medicinal Chemistry, 17 (30). pp. 3503-3513. ISSN 1875-533X

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Abstract

This article highlights recent advances in the discovery of new positive allosteric modulators of the AMPA receptor, excluding compounds of thiadiazine chemotype, most of which were developed by Servier and the University of Lige. The field of AMPA receptor modulators continues to be a fertile area for the discovery of new potential therapeutic agents, and recent years have seen a marked diversification in the range of chemotypes prepared. An overview is also given of the recent key new biological data.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Simon Ward
Date Deposited: 06 Feb 2012 19:55
Last Modified: 13 Jun 2012 13:12
URI: http://sro.sussex.ac.uk/id/eprint/22953
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