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Recent Advances in the Discovery of Selective AMPA Receptor Positive Allosteric Modulators
journal contribution
posted on 2023-06-08, 00:32 authored by Simon E Ward, Mark HarriesThis article highlights recent advances in the discovery of new positive allosteric modulators of the AMPA receptor, excluding compounds of thiadiazine chemotype, most of which were developed by Servier and the University of Lige. The field of AMPA receptor modulators continues to be a fertile area for the discovery of new potential therapeutic agents, and recent years have seen a marked diversification in the range of chemotypes prepared. An overview is also given of the recent key new biological data.
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Publication status
- Published
Journal
Current Medicinal ChemistryISSN
1875-533XExternal DOI
Issue
30Volume
17Page range
3503-3513Pages
11.0Department affiliated with
- Chemistry Publications
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- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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