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A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea
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posted on 2023-06-08, 00:15 authored by Andrei N Lukashkin, Mikhail E Bashtanov, Ian J RussellA laser-diode forms the basis of a displacement sensitive homodyne interferometer suitable for measurements from poorly reflective surfaces. The compact and cost-effective interferometer utilizes the self-mixing effect when laser light reflected from a moving target re-enters the laser cavity and causes phase dependent changes of the lasing intensity. A piezo positioner was used to displace the interferometer with known frequency and amplitude as a basis for real-time calibration of the interferometer's sensitivity. The signal-processing algorithm is described that allows measurements in presence of high amplitude noise leading to variation of the interferometer's operating point. Measurements of sound-induced basilar membrane displacements were made in the intact cochleae of rodents by focusing the laser beam of the interferometer through the transparent round window membrane. The interferometer provides a viable means for making subnanometre mechanical measurements from structures in the inner ears of small mammals, where opening of the cochlea is not practicable.
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Publication status
- Published
Journal
Journal of Neuroscience MethodsISSN
0165-0270External DOI
Issue
2Volume
148Page range
122-129Pages
8.0Department affiliated with
- Biology and Environmental Science Publications
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Principal authorFull text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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