Life can be stressful without ATR

O'Driscoll, Mark (2009) Life can be stressful without ATR. Nature Genetics, 41 (8). pp. 866-868. ISSN 1061-4036

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Abstract

A new study reports the first mouse model for ATR-mutated Seckel syndrome. The mice show phenotypes recapitulating the human disorder and provide insights into how reduced ATR function affects normal embryonic development by increasing replicative stress, ultimately resulting in an accelerated aging phenotype postnatally.

Item Type: Article
Additional Information: GDSC291
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User: Gee Wheatley
Date Deposited: 21 Sep 2009
Last Modified: 19 Mar 2018 15:55
URI: http://sro.sussex.ac.uk/id/eprint/2240
Google Scholar:1 Citations

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