University of Sussex
Browse

File(s) not publicly available

Life can be stressful without ATR.

journal contribution
posted on 2023-06-08, 00:03 authored by Mark O'DriscollMark O'Driscoll
A new study reports the first mouse model for ATR-mutated Seckel syndrome. The mice show phenotypes recapitulating the human disorder and provide insights into how reduced ATR function affects normal embryonic development by increasing replicative stress, ultimately resulting in an accelerated aging phenotype postnatally. © 2009 Nature America, Inc. All rights reserved.

History

Publication status

  • Published

Journal

Nature Genetics

ISSN

10614036

Publisher

Nature Publishing Group

Issue

8

Volume

41

Page range

866-888

Department affiliated with

  • Sussex Centre for Genome Damage Stability Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC