DNA polymerases and repair synthesis in NER in human cells

Lehmann, Alan R. (2011) DNA polymerases and repair synthesis in NER in human cells. DNA Repair, 10 (7). pp. 730-733. ISSN 1568-7864

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Abstract

The late steps of nucleotide excision repair, following incisions to remove the damaged section of DNA, comprise repair synthesis and ligation. In vitro and in vivo studies have shown the size of the repaired patch to be about 30 nucleotides. In vitro studies implicated the replicative polymerases in repair synthesis, but recent in vivo data have shown that several DNA polymerases and ligases are involved in these steps in human cells

Item Type: Article
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
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Depositing User: Alan Lehmann
Date Deposited: 06 Feb 2012 19:34
Last Modified: 24 Jul 2012 08:11
URI: http://sro.sussex.ac.uk/id/eprint/21293
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