The peak to mean pressure decrease ratio: a new method of assessing aortic stenosis

Chambers, J., Rajani, R., Hankins, M. and Cook, R. (2005) The peak to mean pressure decrease ratio: a new method of assessing aortic stenosis. Journal of the American society of Echocardiography, 18 (6). pp. 674-678. ISSN 0894-7317

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Abstract

Background The ratio of peak to mean pressure decrease is a new measure of transaortic continuous waveform shape that could be useful for grading aortic stenosis. Methods We retrospectively analyzed echocardiograms in 163 patients with all grades of aortic stenosis as assessed by the continuity equation. Results The peak to mean pressure decrease ratio was 1.75 (0.14) in mild stenosis, 1.66 (0.13) in moderate stenosis, 1.56 (0.10) in severe stenosis, and 1.57 (0.07) in severe aortic stenosis with left ventricular ejection fraction less than 40%. Receiver operating characteristic curve analysis showed that a threshold of less than 1.50 gave a specificity of 94% against continuity area whereas a ratio less than 1.75 gave a sensitivity of 96%. Conclusion The peak to mean pressure decrease ratio is a simple and quick cue to the likelihood of severe aortic stenosis in patients with low left ventricular ejection fraction when transaortic pressure decreases appear only moderate.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Primary Care and Public Health
Depositing User: Jane Harle
Date Deposited: 24 Oct 2008
Last Modified: 30 Nov 2012 16:53
URI: http://sro.sussex.ac.uk/id/eprint/2049
Google Scholar:14 Citations
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