Chambers, J., Rajani, R., Hankins, M. and Cook, R. (2005) The peak to mean pressure decrease ratio: a new method of assessing aortic stenosis. Journal of the American society of Echocardiography, 18 (6). pp. 674-678. ISSN 0894-7317Full text not available from this repository.
Background The ratio of peak to mean pressure decrease is a new measure of transaortic continuous waveform shape that could be useful for grading aortic stenosis. Methods We retrospectively analyzed echocardiograms in 163 patients with all grades of aortic stenosis as assessed by the continuity equation. Results The peak to mean pressure decrease ratio was 1.75 (0.14) in mild stenosis, 1.66 (0.13) in moderate stenosis, 1.56 (0.10) in severe stenosis, and 1.57 (0.07) in severe aortic stenosis with left ventricular ejection fraction less than 40%. Receiver operating characteristic curve analysis showed that a threshold of less than 1.50 gave a specificity of 94% against continuity area whereas a ratio less than 1.75 gave a sensitivity of 96%. Conclusion The peak to mean pressure decrease ratio is a simple and quick cue to the likelihood of severe aortic stenosis in patients with low left ventricular ejection fraction when transaortic pressure decreases appear only moderate.
|Schools and Departments:||Brighton and Sussex Medical School > Primary Care and Public Health|
|Depositing User:||Jane Harle|
|Date Deposited:||24 Oct 2008|
|Last Modified:||30 Nov 2012 16:53|
|Google Scholar:||14 Citations|