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A convenient approach to (-)-8-epi-swainsonine
journal contribution
posted on 2023-06-07, 21:55 authored by Adrian J Murray, Philip J ParsonsA novel and efficient synthesis of (-)-8-epi-swainsonine (2) is reported. Face-selective diol formation from the bicyclic alkene 3 followed by a stereoselective vinylation of the aldehyde and ring-closing metathesis gave the indolizidine ring system, which was converted into (-)-8-epi-swainsonine (2).
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Publication status
- Published
Journal
SynlettISSN
09365214External DOI
Issue
9Volume
-Page range
1443-1445Department affiliated with
- Chemistry Publications
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- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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