A novel cyclisation strategy for the synthesis of lactonamycin: A new route to highly functionalised heterocyclic rings

Parsons, Philip J, Board, Johnathan, Waters, Alexander J, Hitchcock, Peter B, Wakenhut, Florian and Walter, Daryl S (2006) A novel cyclisation strategy for the synthesis of lactonamycin: A new route to highly functionalised heterocyclic rings. Synlett, - (19). pp. 3243-3246. ISSN 09365214

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Abstract

A novel thermal cascade reaction equivalent to the well-known [2+2+2] cycloaddition has been developed which is clean and reliable and does not involve the use of metal ions. This highly efficient method has been used to construct a model for the synthesis of the antibiotic lactonamycin. The utility of this new sequence for the formation of furans is also reported.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Philip Parsons
Date Deposited: 06 Feb 2012 18:53
Last Modified: 19 Mar 2012 17:19
URI: http://sro.sussex.ac.uk/id/eprint/18802
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