DNA single-strand break repair and spinocerebellar ataxia

Caldecott, Keith (2003) DNA single-strand break repair and spinocerebellar ataxia. Cell, 112 (1). pp. 7-10. ISSN 0092-8674

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Abstract

DNA single-strand break repair (SSBR) is critical for the survival and genetic stability of mammalian cells. Three papers have recently associated mutations in putative human SSBR genes with hereditary spinocerebellar ataxia. The emerging links between SSBR and neurodegenerative disorders are discussed.

Item Type: Article
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User: Keith Caldecott
Date Deposited: 06 Feb 2012 18:35
Last Modified: 17 Jul 2012 11:59
URI: http://sro.sussex.ac.uk/id/eprint/17301
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