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DNA single-strand break repair and spinocerebellar ataxia
DNA single-strand break repair (SSBR) is critical for the survival and genetic stability of mammalian cells. Three papers have recently associated mutations in putative human SSBR genes with hereditary spinocerebellar ataxia. The emerging links between SSBR and neurodegenerative disorders are discussed.
History
Publication status
- Published
Journal
CellISSN
0092-8674Publisher
Cell PressExternal DOI
Issue
1Volume
112Page range
7-10Pages
4.0Department affiliated with
- Sussex Centre for Genome Damage Stability Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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