Parallels between the proximal-distal development of vertebrate and arthropod appendages: homology without an ancestor?

Pueyo-Marques, Jose Ignacio and Couso, Juan Pablo (2005) Parallels between the proximal-distal development of vertebrate and arthropod appendages: homology without an ancestor? Current Opinion in Genetics and Development, 15 (4). pp. 439-446. ISSN 0959-437X

Full text not available from this repository.

Abstract

Evolutionary studies suggest that the limbs of vertebrates and the appendages of arthropods do not share a common origin. However, recent genetic studies show new similarities in their developmental programmes. These similarities might be caused by the independent recruitment of homologous genes for similar functions or by the conservation of an ancestral proximaldistal development programme. This basic programme might have arisen in an ancestral outgrowth and been independently co-opted in vertebrate and arthropod appendages. It has subsequently diverged in both phyla to fine-pattern the limb and to control phylum-specific cellular events. We suggest that although vertebrate limbs and arthropod appendages are not strictly homologous structures they retain remnants of a common ancestral developmental programme.

Item Type: Article
Additional Information: All authors members of my lab
Schools and Departments: School of Life Sciences > Biochemistry
Brighton and Sussex Medical School > Clinical and Experimental Medicine
Depositing User: Jose Pueyo-Marques
Date Deposited: 06 Feb 2012 18:32
Last Modified: 21 Sep 2017 10:42
URI: http://sro.sussex.ac.uk/id/eprint/17013
📧 Request an update