Models wagging the dog: Are Circuits Constructed with Disparate Parameters ?

Nowotny, Thomas, Szucs, Attila, Levi, Rafael and Selverston, Allen I. (2007) Models wagging the dog: Are Circuits Constructed with Disparate Parameters ? Neural Computation, 19 (8). pp. 1985-2003. ISSN 0899-7667

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Abstract

In a recent article, Prinz, Bucher, and Marder (2004) addressed the fundamental question of whether neural systems are built with a fixed blueprint of tightly controlled parameters or in a way in which properties can vary largely from one individual to another, using a database modeling approach. Here, we examine the main conclusion that neural circuits indeed are built with largely varying parameters in the light of our own experimental and modeling observations. We critically discuss the experimental and theoretical evidence, including the general adequacy of database approaches for questions of this kind, and come to the conclusion that the last word for this fundamental question has not yet been spoken.

Item Type: Article
Schools and Departments: School of Engineering and Informatics > Informatics
School of Life Sciences > Biology and Environmental Science
Subjects: Q Science > QA Mathematics > QA0075 Electronic computers. Computer science
Q Science > QP Physiology
Depositing User: Thomas Nowotny
Date Deposited: 07 Mar 2008
Last Modified: 07 Mar 2017 04:24
URI: http://sro.sussex.ac.uk/id/eprint/1553
Google Scholar:11 Citations

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