Outcomes after total versus subtotal abdominal hysterectomy.

Thakar, Ranee, Ayers, Susan, Clarkson, Peter, Stanton, Stuart and Manyonda, Isaac (2002) Outcomes after total versus subtotal abdominal hysterectomy. New England Journal of Medicine, 347 (17). pp. 1318-1325. ISSN 0028-4793

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Abstract

Background: It is uncertain whether subtotal abdominal hysterectomy results in better bladder, bowel, or sexual function than total abdominal hysterectomy. Methods: We conducted a randomized, double-blind trial comparing total and subtotal abdominal hysterectomy in 279 women referred for hysterectomy because of benign disease; most of the women were premenopausal. The main outcomes were measures of bladder, bowel, and sexual function at 12 months. We also evaluated postoperative complications. Results: The rates of urinary frequency (urination more than seven times during the day) were 33 percent in the subtotal-hysterectomy group and 31 percent in the total-hysterectomy group before surgery, and they fell to 24 percent and 20 percent, respectively, at 12 months (P=0.03 for the change over time within each group; P=0.84 for the interaction between the treatment assignment and time). The reduction in nocturia and stress incontinence and the improvement in bladder capacity were similar in the two groups. The frequency of bowel symptoms (as indicated by reported constipation and use of laxatives) and measures of sexual function (including the frequency of intercourse and orgasm and the rating of the sexual relationship with a partner) did not change significantly in either group after surgery. The women in the subtotal-hysterectomy group had a shorter hospital stay (5.2 days, vs. 6.0 in the total-hysterectomy group; P=0.04) and a lower rate of fever (6 percent vs. 19 percent, P<0.001). After subtotal abdominal hysterectomy, 7 percent of women had cyclical bleeding and 2 percent had cervical prolapse. Conclusions: Neither subtotal nor total abdominal hysterectomy adversely affects pelvic organ function at 12 months. Subtotal abdominal hysterectomy results in more rapid recovery and fewer short-term complications but infrequently causes cyclical bleeding or cervical prolapse.

Item Type: Article
Additional Information: Reports results of a RCT run by Thakar, Ayers and Manyonda. Ayers the only psychologist, who advised on measurement, carried out the statistical analysis, and helped write and revise the paper.
Schools and Departments: School of Psychology > Psychology
Depositing User: Susan Ayers
Date Deposited: 06 Feb 2012 15:48
Last Modified: 04 Jul 2012 14:45
URI: http://sro.sussex.ac.uk/id/eprint/14480
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